EphB1 Suppression in Acute Myeloid Leukemia: Regulating the DNA Damage Control System
نویسندگان
چکیده
K.R. Kampen, F.J.G. Scherpen, G. Garcia-Manero, H. Yang, G.J.L. Kaspers, J. Cloos, C.M. Zwaan, M.M. van den Heuvel-Eibrink, S.M. Kornblau, E.S.J.M. De Bont 1 Department of Pediatric Oncology/Hematology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. 2 Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America. 3 Department of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands. 4 Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
منابع مشابه
EphB1 Suppression in Acute Myelogenous Leukemia: Regulating the DNA Damage Control System.
UNLABELLED Loss of ephrin receptor (EphB1) expression may associate with aggressive cancer phenotypes; however, the mechanism of action remains unclear. To gain detailed insight into EphB1 function in acute myelogenous leukemia (AML), comprehensive analysis of EphB1 transcriptional regulation was conducted. In AML cells, EphB1 transcript was inversely correlated with EphB1 promoter methylation....
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